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Replication of association of the apolipoprotein A1-C3-A4 gene cluster with the risk of gout.

Identifieur interne : 001819 ( Main/Exploration ); précédent : 001818; suivant : 001820

Replication of association of the apolipoprotein A1-C3-A4 gene cluster with the risk of gout.

Auteurs : Humaira Rasheed [Pakistan] ; Amanda J. Phipps-Green [Nouvelle-Zélande] ; Ruth Topless [Nouvelle-Zélande] ; Malcolm D. Smith ; Catherine Hill [Australie] ; Susan Lester [Australie] ; Maureen Rischmueller [Australie] ; Matthijs Janssen ; Timothy L. Jansen ; Leo A. Joosten [Pays-Bas] ; Timothy R. Radstake [Pays-Bas] ; Philip L. Riches [Royaume-Uni] ; Anne-Kathrin Tausche [Allemagne] ; Frederic Lioté [France] ; Alexander So [Suisse] ; Andre Van Rij ; Gregory T. Jones ; Sally P. Mccormick [Nouvelle-Zélande] ; Andrew A. Harrison ; Lisa K. Stamp ; Nicola Dalbeth [Nouvelle-Zélande] ; Tony R. Merriman [Nouvelle-Zélande]

Source :

RBID : pubmed:27094595

Descripteurs français

English descriptors

Abstract

Gout is associated with dyslipidaemia. Association of the apolipoprotein A1-C3-A4 gene cluster with gout has previously been reported in a small study. To investigate a possible causal role for this locus in gout, we tested the association of genetic variants from APOA1 (rs670) and APOC3 (rs5128) with gout.

DOI: 10.1093/rheumatology/kew057
PubMed: 27094595


Affiliations:


Links toward previous steps (curation, corpus...)


Le document en format XML

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<name sortKey="Jones, Gregory T" sort="Jones, Gregory T" uniqKey="Jones G" first="Gregory T" last="Jones">Gregory T. Jones</name>
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<name sortKey="Harrison, Andrew A" sort="Harrison, Andrew A" uniqKey="Harrison A" first="Andrew A" last="Harrison">Andrew A. Harrison</name>
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<name sortKey="Stamp, Lisa K" sort="Stamp, Lisa K" uniqKey="Stamp L" first="Lisa K" last="Stamp">Lisa K. Stamp</name>
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<name sortKey="Dalbeth, Nicola" sort="Dalbeth, Nicola" uniqKey="Dalbeth N" first="Nicola" last="Dalbeth">Nicola Dalbeth</name>
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<title xml:lang="en">Replication of association of the apolipoprotein A1-C3-A4 gene cluster with the risk of gout.</title>
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<nlm:affiliation>Department of Biochemistry, University of Otago, Dunedin, New Zealand Department of Chemistry, University of Engineering and Technology, Lahore, Pakistan.</nlm:affiliation>
<country xml:lang="fr">Pakistan</country>
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<name sortKey="Phipps Green, Amanda J" sort="Phipps Green, Amanda J" uniqKey="Phipps Green A" first="Amanda J" last="Phipps-Green">Amanda J. Phipps-Green</name>
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<name sortKey="Topless, Ruth" sort="Topless, Ruth" uniqKey="Topless R" first="Ruth" last="Topless">Ruth Topless</name>
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<name sortKey="Janssen, Matthijs" sort="Janssen, Matthijs" uniqKey="Janssen M" first="Matthijs" last="Janssen">Matthijs Janssen</name>
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<name sortKey="Jansen, Timothy L" sort="Jansen, Timothy L" uniqKey="Jansen T" first="Timothy L" last="Jansen">Timothy L. Jansen</name>
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<name sortKey="Joosten, Leo A" sort="Joosten, Leo A" uniqKey="Joosten L" first="Leo A" last="Joosten">Leo A. Joosten</name>
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<name sortKey="Radstake, Timothy R" sort="Radstake, Timothy R" uniqKey="Radstake T" first="Timothy R" last="Radstake">Timothy R. Radstake</name>
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<name sortKey="Riches, Philip L" sort="Riches, Philip L" uniqKey="Riches P" first="Philip L" last="Riches">Philip L. Riches</name>
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<settlement type="city">Édimbourg</settlement>
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<name sortKey="Tausche, Anne Kathrin" sort="Tausche, Anne Kathrin" uniqKey="Tausche A" first="Anne-Kathrin" last="Tausche">Anne-Kathrin Tausche</name>
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<nlm:affiliation>Department of Rheumatology, University Clinic Carl-Gustav-Carus, Dresden, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Rheumatology, University Clinic Carl-Gustav-Carus, Dresden</wicri:regionArea>
<placeName>
<region type="land" nuts="1">Saxe (Land)</region>
<region type="district" nuts="2">District de Dresde</region>
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<name sortKey="Liote, Frederic" sort="Liote, Frederic" uniqKey="Liote F" first="Frederic" last="Lioté">Frederic Lioté</name>
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<nlm:affiliation>INSERM, UMR-S 1132, Hospital Lariboisière University Paris Diderot (UFR de Médecine), Sorbonne Paris Cité, Paris, F-75205, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
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<name sortKey="So, Alexander" sort="So, Alexander" uniqKey="So A" first="Alexander" last="So">Alexander So</name>
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<nlm:affiliation>DAL, Service of Rheumatology, Laboratory of Rheumatology, University of Lausanne, CHUV, Nestlé 05-5029, Lausanne, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>DAL, Service of Rheumatology, Laboratory of Rheumatology, University of Lausanne, CHUV, Nestlé 05-5029, Lausanne</wicri:regionArea>
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<settlement type="city">Lausanne</settlement>
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<name sortKey="Van Rij, Andre" sort="Van Rij, Andre" uniqKey="Van Rij A" first="Andre" last="Van Rij">Andre Van Rij</name>
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<nlm:affiliation>Department of Surgery, University of Otago, Dunedin.</nlm:affiliation>
<wicri:noCountry code="subField">Dunedin</wicri:noCountry>
</affiliation>
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<name sortKey="Jones, Gregory T" sort="Jones, Gregory T" uniqKey="Jones G" first="Gregory T" last="Jones">Gregory T. Jones</name>
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</affiliation>
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<name sortKey="Mccormick, Sally P" sort="Mccormick, Sally P" uniqKey="Mccormick S" first="Sally P" last="Mccormick">Sally P. Mccormick</name>
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<nlm:affiliation>Department of Biochemistry, University of Otago, Dunedin, New Zealand.</nlm:affiliation>
<country xml:lang="fr">Nouvelle-Zélande</country>
<wicri:regionArea>Department of Biochemistry, University of Otago, Dunedin</wicri:regionArea>
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<author>
<name sortKey="Harrison, Andrew A" sort="Harrison, Andrew A" uniqKey="Harrison A" first="Andrew A" last="Harrison">Andrew A. Harrison</name>
<affiliation>
<nlm:affiliation>Department of Medicine, University of Otago, Wellington.</nlm:affiliation>
<wicri:noCountry code="subField">Wellington</wicri:noCountry>
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<author>
<name sortKey="Stamp, Lisa K" sort="Stamp, Lisa K" uniqKey="Stamp L" first="Lisa K" last="Stamp">Lisa K. Stamp</name>
<affiliation>
<nlm:affiliation>Department of Medicine, University of Otago, Christchurch.</nlm:affiliation>
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<author>
<name sortKey="Dalbeth, Nicola" sort="Dalbeth, Nicola" uniqKey="Dalbeth N" first="Nicola" last="Dalbeth">Nicola Dalbeth</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Medicine, University of Auckland, Auckland, New Zealand.</nlm:affiliation>
<country xml:lang="fr">Nouvelle-Zélande</country>
<wicri:regionArea>Department of Medicine, University of Auckland, Auckland</wicri:regionArea>
<wicri:noRegion>Auckland</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Merriman, Tony R" sort="Merriman, Tony R" uniqKey="Merriman T" first="Tony R" last="Merriman">Tony R. Merriman</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Biochemistry, University of Otago, Dunedin, New Zealand tony.merriman@otago.ac.nz.</nlm:affiliation>
<country wicri:rule="url">Nouvelle-Zélande</country>
<wicri:regionArea>Department of Biochemistry, University of Otago, Dunedin</wicri:regionArea>
<wicri:noRegion>Dunedin</wicri:noRegion>
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</analytic>
<series>
<title level="j">Rheumatology (Oxford, England)</title>
<idno type="eISSN">1462-0332</idno>
<imprint>
<date when="2016" type="published">2016</date>
</imprint>
</series>
</biblStruct>
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<textClass>
<keywords scheme="KwdEn" xml:lang="en">
<term>Adult</term>
<term>Apolipoprotein A-I (genetics)</term>
<term>Apolipoprotein C-III (genetics)</term>
<term>Apolipoproteins C (genetics)</term>
<term>Case-Control Studies</term>
<term>European Continental Ancestry Group (genetics)</term>
<term>Female</term>
<term>Genotype</term>
<term>Gout (genetics)</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Multigene Family (genetics)</term>
<term>Oceanic Ancestry Group (genetics)</term>
<term>Risk Factors</term>
<term>Uric Acid (metabolism)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr">
<term>Acide urique (métabolisme)</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Apolipoprotéine A-I (génétique)</term>
<term>Apolipoprotéine C-III (génétique)</term>
<term>Apolipoprotéines C (génétique)</term>
<term>Facteurs de risque</term>
<term>Famille multigénique (génétique)</term>
<term>Femelle</term>
<term>Goutte (génétique)</term>
<term>Génotype</term>
<term>Humains</term>
<term>Mâle</term>
<term>Population d'origine européenne (génétique)</term>
<term>Population d'origine océanique (génétique)</term>
<term>Études cas-témoins</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en">
<term>Apolipoprotein A-I</term>
<term>Apolipoprotein C-III</term>
<term>Apolipoproteins C</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en">
<term>European Continental Ancestry Group</term>
<term>Gout</term>
<term>Multigene Family</term>
<term>Oceanic Ancestry Group</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr">
<term>Apolipoprotéine A-I</term>
<term>Apolipoprotéine C-III</term>
<term>Apolipoprotéines C</term>
<term>Famille multigénique</term>
<term>Goutte</term>
<term>Population d'origine européenne</term>
<term>Population d'origine océanique</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en">
<term>Uric Acid</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr">
<term>Acide urique</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Adult</term>
<term>Case-Control Studies</term>
<term>Female</term>
<term>Genotype</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Risk Factors</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr">
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Facteurs de risque</term>
<term>Femelle</term>
<term>Génotype</term>
<term>Humains</term>
<term>Mâle</term>
<term>Études cas-témoins</term>
</keywords>
</textClass>
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<front>
<div type="abstract" xml:lang="en">Gout is associated with dyslipidaemia. Association of the apolipoprotein A1-C3-A4 gene cluster with gout has previously been reported in a small study. To investigate a possible causal role for this locus in gout, we tested the association of genetic variants from APOA1 (rs670) and APOC3 (rs5128) with gout.</div>
</front>
</TEI>
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<country>
<li>Allemagne</li>
<li>Australie</li>
<li>France</li>
<li>Nouvelle-Zélande</li>
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<li>District de Dresde</li>
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<name sortKey="Stamp, Lisa K" sort="Stamp, Lisa K" uniqKey="Stamp L" first="Lisa K" last="Stamp">Lisa K. Stamp</name>
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</noRegion>
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<noRegion>
<name sortKey="Phipps Green, Amanda J" sort="Phipps Green, Amanda J" uniqKey="Phipps Green A" first="Amanda J" last="Phipps-Green">Amanda J. Phipps-Green</name>
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<name sortKey="Hill, Catherine" sort="Hill, Catherine" uniqKey="Hill C" first="Catherine" last="Hill">Catherine Hill</name>
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<name sortKey="Joosten, Leo A" sort="Joosten, Leo A" uniqKey="Joosten L" first="Leo A" last="Joosten">Leo A. Joosten</name>
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<name sortKey="Radstake, Timothy R" sort="Radstake, Timothy R" uniqKey="Radstake T" first="Timothy R" last="Radstake">Timothy R. Radstake</name>
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<name sortKey="Riches, Philip L" sort="Riches, Philip L" uniqKey="Riches P" first="Philip L" last="Riches">Philip L. Riches</name>
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